Human studies on potential anticancer and stimulation of the immune system by chaga mushroom are needed. Laboratory show that compounds in chaga can kill cancer cells selectively and stimulate the immune system and chaga may inhibit the progression of some cancers. Studies in humans are needed. Side effects include: Kidney damage/disease: Associated with taking chaga daily for 6 months. It is used as a folk remedy in Russia to treat cancer and In addition, chaga extracts have pro-apoptotic effects against colon, lung, and liver cancer cells. Inotodiol from chaga exerted antitumor effects against cervical cancer cells, In some studies, chaga demonstrated selective apoptosis in tumor cells with no effects on healthy cells. In animal models, it stops the cell growth of melanoma. But no clinical trials have assessed chaga’s safety nor efficacy for disease prevention or for the treatment of cancer, cardiovascular disease, or diabetes. A hot-water extract of chaga exhibited inhibitory and proapoptotic actions against colon cancer cells. Inotodiol, a triterpenoid isolated from chaga, inhibited proliferation of cervical cancer cells and induced apoptosis. Remember that slow progress to good health is better than no progress.
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