Psilocybin is not recommended for individuals with (or who are at risk for) psychotic disorders, such as schizophrenia and bipolar disorder, as psilocybin may be damaging or exacerbating, and may interact with certain medications or patients with cardiovascular issues, because psilocybin can increase blood pressure and heart rate (a preliminary evaluation by the practitioner can help determine if you’re a candidate). Hallucinations are common for a psilocybin session or “trip/journey” and while they may be eye-opening and welcome to a participant, they can also be frightening or disturbing.
These frightening hallucinations are also known as a bad trip, in which you may become anxious, agitated, confused and/or panicked. While this can happen at any dose, it’s safest to start at a low dose and see how that affects you before increasing. Higher doses of 13 milligrams or higher, per Brown University, can lead to: Facial flushing and sweating, slowed sense of time, Feeling separated from your body. Signs of a potential psilocybin overdose include Dizziness, Numbness in parts of the mouth, Shivering or sweating and Nausea.
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