What are Anal Dysplasia and Anal Cancer?

Any kind of abnormal cell changes are called dysplasia. Anal dysplasia is one term used to describe conditions that exist before anal squamous cell carcinoma. Infection with human papilloma virus (HPV) is associated with these changes.  What is anal dysplasia? Dysplasia refers to any kind of abnormal changes in the cells of the body. Anal dysplasia, anal intraepithelial neoplasia (AIN) and anal squamous intraepithelial lesion (SIL) are terms used to describe conditions that occur before the onset of anal squamous cell cancer (SCC).

The anus is located at the end of the intestinal tract. The anus is the part of the rectum that allows stool to pass outside of the body. How is anal dysplasia related to anal cancer? The human papilloma virus (HPV) infects the lowest cell layer of the skin, the basement membrane. For instance, condyloma (warts) are considered to be a form of mild dysplasia. These warts are not cancer, but they do indicate an HPV infection.

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