A famous compound that you can buy off the shelf, animal studies suggest Conjugated Linoleic Acid, or CLA, supplementation may improve insulin sensitivity and blood lipid profiles, decrease body fat, and reduce risks for cancer and cardiovascular disease as well as prevent and treat cancer. Although animal studies suggest CLA has antioxidant properties and may reduce cancer risk, studies in humans are limited and mixed. Therefore, clinical trials to confirm safety and effectiveness are needed.
CLA supplements have been marketed for weight control and to prevent cancer. Animal studies suggest that CLA may play a role to decrease rapid increase in numbers of cancer cells. Studies were done in colon cancer, breast cancer in mice showed anticancer effect but a meta-analysis showed taking CLA did not decrease the risk of breast cancer.
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