Does Indole-3-Carbinol help against cancer?
Indole-3-Carbinol also called I3C, is a phytochemical found in cruciferous vegetables including Brussels sprouts, kale, broccoli, cabbage, and cauliflower. It is known to stimulate detoxifying enzymes in the gut and liver. Because diets high in these vegetables slow cancer growth in animals, I3C is thought to be a good candidate for cancer prevention. Lab studies suggest that I3C may have activity across various tumor types or enhance activity of some chemotherapy drugs. However, other animal studies suggest that I3C might also promote tumor growth. Additional studies and human clinical trials are needed to determine the circumstances under which I3C might be suitable for cancer prevention.
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